Product Name: Methyl gallate
Chemical Formula: C8H8O5
Synonyms: Gallic acid methyl ester, Methyl 3,4,5-trihydroxybenzoate
CAS Number: 99-24-1
Manufacturer Details: Listed per supplier documentation
Recommended Use: Research, chemical synthesis, antioxidant applications
Restrictions on Use: Not for food or pharmaceutical uses without appropriate authorization
Classification: Not classified as a hazardous chemical according to GHS criteria
Signal Word: None
Hazard Statements: May cause mild eye and skin irritation in some individuals; inhalation of dust can trigger coughing and discomfort
Pictograms: None required for this compound
Precautionary Statements: Use personal protection, minimize dust generation, and store in a well-ventilated area
Chemical Name: Methyl gallate
CAS Number: 99-24-1
Percent Composition: 99% or higher (by purity depending on source)
Impurities: Trace amounts of gallic acid, solvents, or unreacted methylating agents
Inhalation: Move person to fresh air, keep comfortable, seek medical attention if symptoms persist
Skin Contact: Wash affected area thoroughly with soap and water, remove contaminated clothing, consult medical attention for prolonged symptoms
Eye Contact: Rinse carefully with running water for at least 15 minutes holding eyelids apart, consult medical help if irritation occurs
Ingestion: Rinse mouth with water, do not induce vomiting, seek medical advice if large quantities are swallowed or if symptoms occur
Suitable Extinguishing Media: Water spray, carbon dioxide (CO2), dry chemical powder, foam
Unsuitable Media: High-pressure water jet
Specific Hazards Arising from the Chemical: Combustion can produce carbon monoxide, carbon dioxide, and irritating fumes
Protective Equipment and Precautions: Firefighters should wear full protective gear and self-contained breathing apparatus; prevent runoff into drains
Personal Precautions: Avoid inhaling dust, provide adequate ventilation, use protective gloves and goggles
Environmental Precautions: Prevent spillage from entering drains or watercourses, contain spill using inert absorbers like vermiculite or sand
Cleanup Methods: Sweep up and place in approved container for disposal, wash spill area thoroughly, dispose of materials in accordance with waste regulations
Handling: Use in well-ventilated settings, avoid dust formation, wear suitable protective clothing, minimize direct contact
Storage: Keep container tightly closed, store in a cool, dry location, protect from light, store away from oxidizing agents
Special Considerations: Only trained personnel should handle large quantities or perform lab-scale synthesis
Exposure Limits: No occupational exposure limits set by OSHA, NIOSH, or ACGIH as of latest reviews
Engineering Controls: Local exhaust ventilation, safety showers, and eye wash stations close to workspace
Personal Protective Equipment: Chemical-resistant gloves (nitrile, latex), laboratory coats, safety goggles or face shield
Hygiene Measures: Avoid eating, drinking, or smoking while handling, wash hands thoroughly after use
Appearance: White to off-white crystalline powder
Odor: Odorless or very slight characteristic odor
Melting Point: 199-203 °C
Boiling Point: Decomposes before boiling
Solubility: Soluble in water, ethanol, methanol, and acetone
pH (1% Solution): Around 5.5 to 6.5
Vapor Pressure: Not available (very low, negligible under normal conditions)
Density: ~1.5 g/cm3
Partition Coefficient (log Kow): 0.7 (estimated)
Chemical Stability: Stable under standard handling and storage conditions
Reactivity: Not reactive in normal usage; sensitive to strong oxidizing agents
Hazardous Reactions: No dangerous reactions known under recommended conditions
Decomposition Products: Carbon oxides, irritating fumes on thermal decomposition
Conditions to Avoid: Excess heat, moisture, sources of ignition, incompatible chemicals
Acute Toxicity: Low acute oral toxicity, LD50 (mouse) > 5,000 mg/kg
Skin Corrosion/Irritation: Mild irritant in sensitive individuals
Eye Damage/Irritation: Mild irritant if particles enter eyes
Respiratory Sensitization: Dust may cause mild respiratory irritation
Carcinogenicity, Mutagenicity, Reproductive Toxicity: No components identified as carcinogens, mutagens, or reproductive toxicants by NTP, IARC, or OSHA
Other Effects: No data suggesting chronic or delayed effects from anticipated routes of exposure
Ecotoxicity: Very low acute aquatic toxicity; not classified as hazardous to aquatic life
Persistence and Degradability: Biodegradable in the environment; subject to microbial degradation
Bioaccumulation Potential: Low; determined by low log Kow value
Mobility in Soil: Likely to exhibit moderate to high mobility due to water solubility
Other Information: No evidence for bioaccumulation or disruption of aquatic food chains at normal release levels
Waste Disposal Methods: Collect and place material in tightly sealed containers for disposal as chemical waste; comply with local regulations
Empty Containers: Rinse thoroughly before disposal or recycling, puncture to prevent reuse
Special Considerations: Do not dispose via sewage system, avoid release to the environment in uncontrolled quantities
UN Number: Not regulated as a dangerous good for transport
Proper Shipping Name: Not classified
Hazard Class: Non-hazardous material
Packing Group: Not applicable
Environmental Hazards: None identified for transportation
Special Precautions for Transport: Secure packaging against moisture and breakage, avoid temperature extremes
TSCA Status: Listed and permitted for research and industrial applications
REACH Registration: Registered or exempt (verify compliance with local requirements)
SARA Title III: No listed components under Section 302, 313
WHMIS Classification (Canada): Not a controlled product under WHMIS 2015
California Proposition 65: No ingredients listed under Proposition 65
Other National/International Regulations: No restrictions recognized in GHS-aligned jurisdictions; always check local policies for use and disposal
